Back to those studies

I did another quick google search to see if anything new has popped up on dealing with thin uterine lining especially after chemo and total body radiation.

Nothing new. But I did revisit this article published by Biomed Research International in 2014.

The paper mentions one study that had success with a mix of pentoxifylline (PTX) and tocopherol (Vitamin E) in increasing blood flow to the uterus that had been damaged due to radiation.

One study only looked at 6 women who took hormone replacement but also supplemented with 400mg PTX and 500IU of Vitamin E twice a day for 9 months. “Improvements in endometrial thickness, ( 6.2 v 3.2 mm), myometrial dimensions (44 [±5] x30 [±3] x20 [±2] versus 30 [±7]x  22 [±3] x16 [±2] mm), and diastolic uterine artery flow were observed”.

In another case 18 patients who had endometrial thickness of < 6mm took the same combo of PTX and Vitamin E for 6 months. Of these women five became pregnant during the study, two of those women had previously experience total body irradiation. For all of them, endometrial thickness increased from 4.9 to 6.2 on average.

Even though these sample sizes are really small, I feel that given the evidence it can’t hurt for me to try taking the combo of PTX and Vitamin E now to start boosting blood flow. I have emailed the clinic coordinator to see if she can get in touch with Dr. Go to see if he will agree to write me a Rx for PTX.

The paper also confirmed that I am at higher risk for pregnancy complications.  “Analysis of singleton pregnancies has shown that these women (who previously had total body irradiation) had significantly higher rates of caesarean section (42% versus 16%), preterm delivery (20% versus 6%), and low birth weight singleton offspring (23% versus 6%) compared to the general population”. Hence the recommendation that I be monitored as a high risk pregnancy when the time comes. In that case, at least we will know what to look for and can hopefully address it before it becomes an issue.

In my highly unscientific and totally non-expert opinion, most of these complications can be linked to the damage to the normal blood flow to the uterus.

Without adequate blood flow, the uterine lining will not thicken, any growing baby will not get sufficient nutrients through the blood to be able to grow sufficiently and to term. So it all boils down to boosting blood flow to boost lining and create a more hospitable environment for the embryo.

In previous cycles I have tried increasing my estrace dosage (using both pills and patches) alone but this was minimally helpful. The last round of mock cycles I also added in acupuncture, 400IU Vitamin E, as well as used Sildenafil, and my lining improved. So maybe adding the PTX and upping my Vitamin E dosage will be the last little boost I need to get up to 7mm.

I have already started supplementing with Vitamin E 400IU a day in anticipation. I am now considering increasing my dosage to 1000IU a day and starting PTX. So long as I am given the go ahead by Dr. Go.

Conducting my own little study of 1.

 

 

 

 

 

 

 

 

All is well

Two things:

  1. Hysteroscopy went off without a hitch. They said everything looks fine. No issues. And I was back at work in an hour and a half. Things have calmed down a bit at work and I feel like I can breathe again.
  2. DEB USA just sent me this: “…this email is to inform you that your shipment has been initiated.  Please allow two weeks (more or less) for your shipment to arrive at your practice, which will be on or by, 03/09/2017.” Eeep!

Ducks are getting in a row quite nicely now.

giphy-4

 

Hysteroscopy time

Work has been insane this week. Actually this whole month has. Last night I didn’t get home till after 8pm. 

Today we are finalizing a big financing deal that closes in three days, so it is all hands on deck to ensure everything gets signed off without a hitch. 

Naturally this is the perfect time to fit in my hysteroscopy appointment. At 1:30 today.  If I cancelled today I would likely have to wait till my next cycle (it has to be completed between days 5-12 of my cycle). If the results reveal some abnormality that needs to be taken care of then I will need more time to deal with that. So I think it is best to go ahead as planned and hope nothing comes up in the 2hrs I’m gone from the office. I will definitely need to go back in to work afterwards. And probably stay late tonight to catch up to all the other work that has taken a back seat to the financing deal. 

I let the president know I need to step out for a doctors apt. He’s normally pretty good about that as long as I give him notice. But it is a stressful time for him so who knows? 

Hopefully things will work out fine at work and the results of the hysteroscopy will come back all clear. 

#MicroblogMonday: Pre-(IVF)game rituals

Microblog_MondaysApart from the obvious incessant googling of every single thing that can go wrong, I am thinking I need to have some sort of ritual that is just for me and to help me prepare for the challenging summer I am about to have.

Of course with the expense of this cycle I need to come up with ideas that are budget friendly. I would have loved to have had one more getaway before we are in the thick of it. But we just had a pretty luxurious vacation in Hawaii in January so we are all tapped out for vacation funds for a while. Plus I need things that can occupy me until April.

So what can I do to help mentally and physically prepare myself for my first real IVF cycle? Ideas welcome.

For starters since I will likely go through a lot of physical changes (hopefully the good pregnancy kind, but definitely the yucky hormonal weight gain that comes with the excessive quantities of estrogen), I have decided to start wearing all my tight sexy outfits for the next few weeks while I still can. I have been taking good care of myself and feel healthy and look good. So why not flaunt what I got while I still have it? I am sure I will have opportunities to get my sexy on afterwards too, but I know that during the process the thought of putting on that pencil skirt, tight dress or even tucking in a shirt for work will just not be as appealing so I will take advantage now while I still feel good about my body.

And then there is the usual being healthy stuff.

I work out regularly. Lifting weights to build strong muscles, and will start training for another 10k run that both DH and I will (hopefully) do in May. That will also help with the above looking sexy bit, for a little while at least. And I just feel so much happier when I am working out regularly. It is a great way to clear my mind and just focus on the moment. I also find I eat healthier if I have been working out. So continuing more of the same until I have to stop for medical reasons.

I want to start getting into a regular yoga routine at home. I am a certified yoga teacher, but I stopped teaching last year due to scheduling issues and a heavier workload at work. I would at the very least like to start getting back into the routine of my own practice. I probably wont look for another teaching gig for a little while, but I do want to start researching some fertility yoga poses and perhaps build my practice around that over the next few months. This one is a bit more challenging as when I get home I am just so exhausted that all I want to do is veg in front of the TV. But I will try to push myself to at least start stretching in front of the TV a few times a week.

Speaking of, I love my weekly TV escapes. Monday night Bachelor is a must see for me. I just love watching the crazy every week. I even have DH hooked (even though he claims it is so stupid, and it is). Perhaps I can make it a Monday night Bachelor and yoga practice? Walking Dead is also back now, and Game of Thrones is right around the corner. Lots to look forward to. It is nice to be able to escape from thinking about IF 24/7.

I think this will all help me to stay sane before we are full speed ahead. Any other ideas?


Get more #MicroblogMonday posts here

 

 

 

 

 

AF

Is it pretty embarrassing that only until recently (like a few months ago) did I find out that when people say ‘AF’ on social media they actually mean ‘as f@&k’ not ‘aunt flow’?

  • “Feel hot AF”
  • “That shit is painful AF”
  • “He’s fine AF”

Yup. I’m an idiot.

Telling my notary

So apparently the contract with DEB USA needs to be signed in front of a notary. Which of course means I have to actually tell them what they are signing. Not to mention the form itself has the DEB USA logo on it right at the top of the page.

Luckily as a lawyer, I am also a notary. Not so luckily I can’t notarize my own signature. A bit of a conflict of interest there. I could find a random stranger to notarize my egg donation forms. But then I have to tell a random stranger that I am going through DE IVF. Luckily as a lawyer I have many lawyers as good friends. One such friend works in the next building over.

So basically another good friend now knows about our DE IVF journey. And I didn’t have to tell a random stranger.

Tomorrow we send the forms and the money to DEB USA.

Going down that rabbit hole.